Birthdate

08.06.1950

Organization

Belarusian Research & Production Center for Transfusiology and Medical Biotechnologies

Position

Senior Reseacher, Professor

Research specialization

Research area

Medical Biotechnology

Research specialization

Cellular Therapy
Immunology

Career

1978-1997 - junior researcher, senior researcher; head of Laboratory of Immunodiagnostics & Immunotherapy in Research Institute for Blood Transfusion.
1987 - PhD in immunology
1995 - Doctor of Sciences in Immunology
1997-2004- Deputy Director for Research of Belarusian Center for Pediatric Oncology & Hematology.
2004 - Professor for "Clinical Medicine"
2004-2011 - Director of Research & Production Center for Hematology & Transfusiology
2011- present time - senior researcher, Laboratory for biology and genetic of stem cells, Research & Production Center for Transfusiology & Medical BioTechnologies

Scientific activities

Projects

01.09.2001 - 31.01.2005 Development of the computer-based system for prognostic risk factors analysis to select adequate therapy of childhood acute leukemias. Funded by ISTC, Project B-522.
01.01.2006 - 31.12.2010 Evaluation of phenotype, capacity for proliferation and differentiation in vitro, gene transfer, safety in experimental conditions for transplantation of stem cells from human bone marrow, mobilized peripheral blood and cord blood. Funded by Ministry of Health of Belarus
2011 - 2013 Development the technology of hematopoietic stem cell expansion from placenta and cord blood sources. Evaluation and comparison their proliferation and differentiation in vitro. Funded by Parliament of Belarus and Russia.

Publications

1. Lapotko D, Lukianova E, Potapnev M, Aleinikova O, Oraevsky A. Method of laser activated nano-thermolysis for elimination of tumor cells.
Cancer Lett. 2006; 239(1): 36-45..
2. Meleshko AN, Belevtsev MV, Savitskaja TV, Potapnev MP. The incidence of T-cell receptor gene rearrangements in childhood B-lineage acute lymphoblastic leukemia is related to immunophenotype and fusion oncogene expression. Leuk Res. 2006.-V30 (7):795-800.
3. T.Uglova, O.Aleinikova, M.Potapnev, I.Tom, O.Krasko. Prediction the Outcome of Induction Therapy of Childhood Acute Myeloid Leukemia// Annals of Hematology. – 2006, v .85.-Р. 23
4. Kuzmenok OI, Dvoryanchikov GA, Ponomareva EN, Goncharov AA, Fomin IK, Lee ST, Sanberg PR, Potapnev MP. Myasthenia gravis accompanied by thymomas not related to foamy virus genome in belarusian's patients.
Int J Neurosci. 2007 Nov;117(11):1603-10.
5. Shakhbazau A., Shcharbin D., Seviaryn I., Goncharova N., Kosmacheva S., Potapnev M., Gabara B., Ionov M., Bryszewska M. Use of polyamidoamine dendrimera to engineer BDNG-producing human mesenchymal stem cells // Molecular Biology Reports 2010.- Vol.37 (4): 2003-2008.
6. Petyovka N.V., Goncharova N.V., Seviaryn I.M., S.M. Kosmacheva, M.P.Potapnev In vitro expansion and lineage commitment of the human umbilical cord blood myeloid progenitors // Abstracts of “5th Raisa Gorbacheva Memorial Meeting on Hematopoietic Stem Cell Transplantation”, Saint Petersburg, Russia, September 18-20, 2011 / Cellular Therapy and Transplantation (CTT), 2011.-Vol 3, No.2.-P.80.
7. D. Shcharbin, V. Dzmitruk, A. Shakhbazau , N. Goncharova, I. Seviaryn, S. Kosmacheva, M. Potapnev, E. Pedziwiatr-Werbicka, M. Bryszewska, M. Talabaev, A. Chernov, V. Kulchitsky, A.-M. Caminade and J.-P. Majoral. Fourth Generation Phosphorus-Containing Dendrimers: Prospective Drug and Gene Delivery Carrier // Pharmaceutics.- 2011.- Vol. 3, №. 3.-С. 458-473.
8. Shakhbazau A, Shcharbin D, Petyovka N., Goncharova N., Seviaryn I, Kosmacheva S, Bryszewska M., Potapnev M. Non-virally modified human mesenchymal stem cells produce ciliary neurotrophic Factor in biodegradable fibrin-based 3D scaffolds // J Pharmaceutical Sciences.- 2012.- Vol.101, № 4.- C. 1546 – 1554.
9. Grinev V. V., Seviaryn I. N., Posrednik D. V., Kosmacheva S. M., Potapnev M. P. Highly efficient transfer and stable expression of two genes upon lentivirus transduction of mesenchymal stem cells from human bone marrow // Russian Journal of Genetics. – 2012. – Vol. 48, № 3. – P. 336-346.

Patents

2012 "The method to obtain antistaphylococcal blood plasma" Eurasian patent # 016268

Contact data

220053, Minsk, Dolginovsky tract, 160
tel.: +375 17 2898844
email: mpotapnev@yandex.ru